5/24/2025
Last update
5/24/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.9
USERS' SCORE
Good
Based on 19 Reviews
8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
8
We investigated how long-term exposure to urban air pollution affects the recovery from ischemic stroke in mice. Our findings showed that breathing in fine particulate matter increases neuroinflammation and cardiac injury, leading to higher mortality rates after a stroke.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Read More
8
Vitamin E intake and heart health
We investigated how dietary vitamin E intake relates to cardiovascular disease and mortality using data from over 39,000 participants in the NHANES study from 2003 to 2018.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Read More
8
We examined various studies comparing tocotrienol and tocopherol, types of vitamin E, in managing atherosclerotic cardiovascular disease. After reviewing 516 articles, we found that tocotrienol significantly reduced cholesterol and inflammatory markers, showing promising benefits for heart health. In contrast, tocopherol presented mixed results, sometimes increasing mortality risk. This suggests that tocotrienol may be a safer and more effective choice for improving cardiovascular health.
Read More
Most Useful Reviews
9
Reproductive health
7 people found this helpful
Vitamin E is vital for cellular protection against damage from free radicals, strengthens immunity, promotes blood vessel health, and reduces thrombus formation. It assists in reproductive health and can alleviate symptoms related to cardiovascular disease and menopause.
Read More
9
Combine for efficacy
3 people found this helpful
This vitamin E is excellent and affordable. It’s a powerful antioxidant that supports immunity and cardiovascular health, particularly when combined with vitamin C and A. I recommend it highly for managing cholesterol levels and overall health.
Read More
9
Fights heart disease
1 people found this helpful
Vitamin E has received much attention for its role in combating coronary heart disease. Its various forms are essential for overall heart health.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.9
- All Researches
8
Antioxidants reduce CVD mortality risk
We investigated the connection between dietary antioxidants, including vitamin E, and mortality risks in patients with cardiovascular disease (CVD). In our research with 1,395 participants, we found that higher levels of antioxidants were linked to decreased all-cause and cardiovascular-cause deaths.
Specifically, vitamins like C and E showed beneficial effects. This suggests that boosting our antioxidant intake could be a helpful strategy for improving health outcomes in those with CVD.
Specifically, vitamins like C and E showed beneficial effects. This suggests that boosting our antioxidant intake could be a helpful strategy for improving health outcomes in those with CVD.
Read More
8
We investigated how long-term exposure to urban air pollution affects the recovery from ischemic stroke in mice. Our findings showed that breathing in fine particulate matter increases neuroinflammation and cardiac injury, leading to higher mortality rates after a stroke.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Interestingly, incorporating a vitamin E-rich diet helped reduce cardiac damage and lung inflammation caused by this exposure. We saw a noteworthy improvement in survival rates among mice with ischemic strokes who received the vitamin E, highlighting its potential protective effects against the dangers of urban air pollution.
Read More
8
Higher vitamin E linked to decreased mortality
In this extensive study of over 16,000 adults with hypertension, we found that higher dietary antioxidant intake, including vitamin E, is linked to a reduced risk of deaths from all causes and specifically from cardiovascular disease (CVD).
Over about seven years of following participants, those with the highest levels of vitamin E intake showed a lower likelihood of CVD mortality compared to those with lower intakes.
While these findings are promising, further research is still needed to solidify these conclusions.
Over about seven years of following participants, those with the highest levels of vitamin E intake showed a lower likelihood of CVD mortality compared to those with lower intakes.
While these findings are promising, further research is still needed to solidify these conclusions.
Read More
8
Vitamin E intake and heart health
We investigated how dietary vitamin E intake relates to cardiovascular disease and mortality using data from over 39,000 participants in the NHANES study from 2003 to 2018.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Read More
8
We examined various studies comparing tocotrienol and tocopherol, types of vitamin E, in managing atherosclerotic cardiovascular disease. After reviewing 516 articles, we found that tocotrienol significantly reduced cholesterol and inflammatory markers, showing promising benefits for heart health. In contrast, tocopherol presented mixed results, sometimes increasing mortality risk. This suggests that tocotrienol may be a safer and more effective choice for improving cardiovascular health.
Read More
User Reviews
USERS' SCORE
Good
Based on 19 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reproductive health
7 people found this helpful
Vitamin E is vital for cellular protection against damage from free radicals, strengthens immunity, promotes blood vessel health, and reduces thrombus formation. It assists in reproductive health and can alleviate symptoms related to cardiovascular disease and menopause.
Read More
9
Combine for efficacy
3 people found this helpful
This vitamin E is excellent and affordable. It’s a powerful antioxidant that supports immunity and cardiovascular health, particularly when combined with vitamin C and A. I recommend it highly for managing cholesterol levels and overall health.
Read More
9
Fights heart disease
1 people found this helpful
Vitamin E has received much attention for its role in combating coronary heart disease. Its various forms are essential for overall heart health.
Read More
7.5
Guideline values improved
1 people found this helpful
After two months of taking "IRON" + "Natural E400", my guideline values improved by 14%. Initially, I experienced dizziness, but now I feel less fatigued, which is beneficial for managing cardiovascular disease.
Read More
7.5
Cell protection
19 people found this helpful
Vitamin E is a fantastic natural supplement, essential for adults. It acts as an antioxidant, safeguarding cell membranes and promoting healthy blood vessel function, particularly in small capillaries. This is vital for those with cardiovascular disease and helps ease respiratory illness.
Read More
Frequently Asked Questions
6
Enhanced blood flow
After increasing my Vitamin E intake, I noticed improved blood flow and less coldness, which is beneficial for my cardiovascular health.
7.5
Guideline values improved
1 people found this helpful
After two months of taking "IRON" + "Natural E400", my guideline values improved by 14%. Initially, I experienced dizziness, but now I feel less fatigued, which is beneficial for managing cardiovascular disease.
6
Start low dosage
4 people found this helpful
My mother, with cardiovascular disease, takes vitamin E cautiously. Starting with a low dose and gradually increasing has been effective. After half a year, she reached 1200mg, aiming for 1500-2000mg. I also benefit from it daily.
9
Combine for efficacy
3 people found this helpful
This vitamin E is excellent and affordable. It’s a powerful antioxidant that supports immunity and cardiovascular health, particularly when combined with vitamin C and A. I recommend it highly for managing cholesterol levels and overall health.
6
Eased shoulder pain
1 people found this helpful
Since starting to take Vitamin E, my shoulder pain has lessened, and my motion range has increased, positively impacting my cardiovascular health.
8
Vitamin E intake and heart health
We investigated how dietary vitamin E intake relates to cardiovascular disease and mortality using data from over 39,000 participants in the NHANES study from 2003 to 2018.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
Our findings showed that people with higher vitamin E consumption had a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E were associated with a 43% lower odds of cardiovascular issues compared to those with lower intakes. Yet, results for cardiovascular-related deaths showed less certainty.
This suggests that including vitamin E-rich foods in our diets could have positive effects on heart health and longevity.
8
Higher vitamin E linked to decreased mortality
In this extensive study of over 16,000 adults with hypertension, we found that higher dietary antioxidant intake, including vitamin E, is linked to a reduced risk of deaths from all causes and specifically from cardiovascular disease (CVD).
Over about seven years of following participants, those with the highest levels of vitamin E intake showed a lower likelihood of CVD mortality compared to those with lower intakes.
While these findings are promising, further research is still needed to solidify these conclusions.
Over about seven years of following participants, those with the highest levels of vitamin E intake showed a lower likelihood of CVD mortality compared to those with lower intakes.
While these findings are promising, further research is still needed to solidify these conclusions.
2
We explored how certain antioxidants, especially vitamin E (α-tocopherol), relate to cardiovascular disease risk using a two-sample Mendelian randomization approach.
Surprisingly, our findings suggest that higher levels of α-tocopherol might be associated with an increased risk of serious heart conditions like myocardial infarction and arrhythmias.
Similarly, retinol was linked to greater risks for cardiomyopathy and heart failure. This challenges the common perception of antioxidants as solely beneficial, indicating that some may actually pose health risks.
More research is needed to fully understand these relationships and their implications for our dietary choices.
Surprisingly, our findings suggest that higher levels of α-tocopherol might be associated with an increased risk of serious heart conditions like myocardial infarction and arrhythmias.
Similarly, retinol was linked to greater risks for cardiomyopathy and heart failure. This challenges the common perception of antioxidants as solely beneficial, indicating that some may actually pose health risks.
More research is needed to fully understand these relationships and their implications for our dietary choices.
8
We examined various studies comparing tocotrienol and tocopherol, types of vitamin E, in managing atherosclerotic cardiovascular disease. After reviewing 516 articles, we found that tocotrienol significantly reduced cholesterol and inflammatory markers, showing promising benefits for heart health. In contrast, tocopherol presented mixed results, sometimes increasing mortality risk. This suggests that tocotrienol may be a safer and more effective choice for improving cardiovascular health.
References
- Hu X, Zhao Z, An Q, Li Y, Wang B. Association of independent dietary antioxidant intake, and CDAI level with risks of all-cause and cardiovascular-cause death among population with cardiovascular disease. BMC Public Health. 2025;25:1327. 10.1186/s12889-025-22481-1
- Yang R, Lv M, Yang X, Zhai S. A Mendelian randomized study of circulating antioxidants in the diet and risk of cardiovascular disease. Sci Rep. 2025;15:10341. 10.1038/s41598-025-94369-4
- Czlapka-Matyasik M, Wadolowska L, Gut P, Gramza-Michałowska A. Changes in Oxidative Stress, Inflammatory Markers, and Lipid Profile After a 6-Week High-Antioxidant-Capacity Dietary Intervention in CVD Patients. Nutrients. 2025;17. 10.3390/nu17050806
- Ishihara N, Tanaka M, Namba K, Kawano S, Nishimura S, et al. Long-term exposure to urban particulate matter exacerbates mortality after ischemic stroke in mice. J Toxicol Sci. 2025;50:147. 10.2131/jts.50.147
- Zhao S, Cao Y, Liu H, Liu A. Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study. Nutr J. 2025;24:14. 10.1186/s12937-024-01062-9
- Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. 10.1016/j.ijcrp.2024.200340
- Ren W, Li Y, Lu C, Liu S, Shao Y, et al. Comprehensive assessment on the association of dietary vitamins with all-cause and cardiovascular mortality among individuals with prediabetes: evidence from NHANES 1999-2018. Food Funct. 2024;15:10037. 10.1039/d4fo02893g
- Li B, Hu M, Ma Y, Sun X, Wu D, et al. Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease. Sci Rep. 2024;14:19960. 10.1038/s41598-024-68413-8
- Wang Y, Han L, Ling S, Sha Y, Sun H. Dietary intake of potassium, vitamin E, and vitamin C emerges as the most significant predictors of cardiovascular disease risk in adults. Medicine (Baltimore). 2024;103:e39180. 10.1097/MD.0000000000039180
- Rafique S, Khan DA, Farhat K, Khan MA, Noor M, et al. Comparative efficacy of tocotrienol and tocopherol (vitamin E) on atherosclerotic cardiovascular diseases in humans. J Pak Med Assoc. 2024;74:1124. 10.47391/JPMA.9227
- Sun Y, Zhang H, Qi G, Tian W. Nutrient deficiency patterns and all-cause and cardiovascular mortality in older adults with hypertension: a latent class analysis. BMC Public Health. 2024;24:1551. 10.1186/s12889-024-19003-w
- Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. 10.2147/CIA.S461821
- Yakoubi S. Synergistic integration of deep learning with protein docking in cardiovascular disease treatment strategies. IUBMB Life. 2024;76:666. 10.1002/iub.2819
- Liu C, Liang D. Association between Dietary Vitamin E Intake and the Risk of Hypertension in US Adults. Curr Vasc Pharmacol. 2024;22:391. 10.2174/0115701611297956240425115501
